Chlamydia Trachomatis Essay -- Essays Papers

Chlamydia TrachomatisIntroduction Chlamydia Trachomatis is the organism responsible for diseases such as trachoma and the STD Chlamydia. Chlamydia is the more or less common STD in the United States, with about 4 million new cases diagnosed every year.The Organism & its Life Cycle Chlamydia ar defy intra cellular phoneular parasites, and are among the smallest living organisms. There are two stages in the life of Chlamydia elementary bodies and reticulate bodies. Another feature of Chlamydia is that they are unable(p) to synthesize their own energy (ATP) and are completely dependent on their waiter for energy. The organism is in the elementary stage of its life when it encounters its multitude and is taken up by phagocytosis. It prevents the fusion of the phagosome and lysosome this is what normally kills pathogens. Once the phagolysosome fundamental law is stopped, the bacteria secrete glycogen and transform into the reticulate body. Reticulate bodies prevail their energy b y sending forth straw-like structures into the host cell cytoplasm, and they allot by binary fission. Each phagolysosome produces about 100-1000 reticulate bodies.Virulence Factors The cell wall of Chlamydia has been characterized as gram negative with a notable discrepancy it lacks muramic acid that is found in the cell walls of most other bacteria. This makes Chlamydia yucky to _-lactam antibiotics such as penicillin, because such antibiotics disrupt the typical cell wall, which includes muramic acid. beingness gram-negative, it also contains LPS, which helps cause damage to the hosts body(mainly due to the hosts immune response). Once inside the host, chlamydia bind sialic acid receptors, which are usually found in mucous-rich environments. Antigenic variation is ... ...nant women and neonates (that are give with Chlamydia), erythromycin is the drug of choice. Chlamydia may be difficult to completely eradicate, simply in the past few years, the incidence rates have been st eady, and with prep and spreading information about it, we can attack the overwhelming incidence rate and curb the spread of Chlamydia.References1) University of Wisconsin. http//www.bact.wisc.edu/Bact330/lecturechlamydia2) CDC. Recommendations for the Prevention and Management of Chlamydia trachomatis Infections, 1993 http//www.cdc.gov/mmwr/preview/mmwrhtml/00021622.htm3) Schaechter, Engleberg, Eisenstein, and Gerald Medoff (1999). Mechanisms of microbial Disease. Third Edition. Lippincott Williams and Wilkins, Philadelphia.4) MedlinePlus Medical Encyclopedia. http//www.nlm.nih.gov/medlineplus/ency/article/001345.htm